| Bioactivity | Beacon (47-73) is a C-terminal peptide fragment 47-73 of Beacon, and Beacon is a protein of 73 amino acid. Beacon (47-73) can be used for metabolic syndrome research[1][2]. |
| Invitro | A 3-h exposure to Beacon (47-73) is ineffective, but prolonged (24 and 96 h) exposures significantly lowered basal corticosterone and cortisol secretion from cultured rat and human zona fasciculata/reticularis (ZF/R) cells, respectively. Moreover, Beacon (47-73) (400 nM) counteracted the secretagogue action of 10 nM ACTH on cultured cells. The 96-h exposure to Beacon (47-73) concentration-dependently decreases basal proliferation rate of cultured cells, without inducing significant changes in the number of apoptotic and necrotic cells. Beacon (400 nM) significantly inhibits the proliferogenic effect of 10 nM Adrenomedullin[1]. |
| Name | Beacon (47-73) |
| CAS | 681153-68-4 |
| Shortening | WYTIFKDHVSLGDYEIHDGMNLELYYQ |
| Formula | C156H217N35O46S |
| Molar Mass | 3350.66 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Beacon (47-73)
CAS: 681153-68-4 F: C156H217N35O46S W: 3350.66
Beacon (47-73) is a C-terminal peptide fragment 47-73 of Beacon, and Beacon is a protein of 73 amino acid. Beacon (47-73
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