| Bioactivity | Bcl-2/Mcl-1-IN-4 (compound 20) is a dual inhibitor targeting Bcl-2 (Ki=0.49 μM) and Mcl-1 (Ki=0.51 μM). Bcl-2/Mcl-1-IN-4 significantly inhibits cancer cell proliferation and effectively induces apoptosis in U937 cells. Bcl-2/Mcl-1-IN-4 can be used in cancer research[1]. |
| Formula | C34H27BrN4O8S2 |
| Molar Mass | 763.63 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Jiabing Long, et al. "Discovery and development of thiazolidine-2, 4-dione derivatives as Bcl-2/Mcl-1 dual inhibitors." Bioorganic Chemistry (2024): 107687. |