Bioactivity | Bay Y5959 is a potent calcium channel agonist. Bay Y5959 binds to the DHP receptor in a voltage-dependent manner increases both the mean open time and the mean closed time of the Ca-channel. Bay Y5959 has the potential for the research of congestive heart failure, arrhythmic[1][2]. |
CAS | 146136-94-9 |
Formula | C26H24N4O2 |
Molar Mass | 424.49 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Pu J, et al. Effects of Bay Y5959 on Ca2+ currents and intracellular Ca2+ in cells that have survived in the epicardial border of the infarcted canine heart. J Cardiovasc Pharmacol. 1999 Jun;33(6):929-37. [2]. Bechem M, et al. A new type of Ca-channel modulation by a novel class of 1,4-dihydropyridines. Life Sci. 1997;60(2):107-18. |