| Bioactivity | Barbadin is a novel and selective β-arrestin/β2-adaptin interaction inhibitor, has IC50 values of 19.1 μM for β-arrestin1 and 15.6 μM for β-arrestin2. Barbadin blocks agonist-promoted endocytosis of the prototypical β2-adrenergic, V2-vasopressin and angiotensin-II type-1 receptors. Barbadin can induce apoptosis[1][2]. | |||||||||
| Invitro | Barbadin (4 h) treatment reduces cell viability and induces apoptosis[2].Barbadin (2 h) treatment arrests breast cancer cells in G0/G1 phase[2]. Apoptosis Analysis[2] Cell Line: | |||||||||
| Name | Barbadin | |||||||||
| CAS | 356568-70-2 | |||||||||
| Formula | C19H15N3OS | |||||||||
| Molar Mass | 333.41 | |||||||||
| Transport | Room temperature in continental US; may vary elsewhere. | |||||||||
| Storage |
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