PeptideDB

Bamocaftor

CAS: 2204245-48-5 F: C28H32F3N5O4S W: 591.64

Bamocaftor (VX-659) is a cystic fibrosis transmembrane conductance regulator (CFTR) corrector designed to restore F508de
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This product is for research use only, not for human use. We do not sell to patients.

Bioactivity Bamocaftor (VX-659) is a cystic fibrosis transmembrane conductance regulator (CFTR) corrector designed to restore F508del-CFTR protein function. Bamocaftor can be used combine with Tezacaftor and Ivacaftor in cystic fibrosis research[1].
Invitro Bamocaftor is a CFTR corrector designed to restore F508del-CFTR protein function[1].
Name Bamocaftor
CAS 2204245-48-5
Formula C28H32F3N5O4S
Molar Mass 591.64
Appearance Solid
Transport Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Reference [1]. Ghelani DP, et al. Emerging Cystic Fibrosis Transmembrane Conductance Regulator Modulators as New Drugs for Cystic Fibrosis: A Portrait of in Vitro Pharmacology and Clinical Translation.