PeptideDB

Bafisontamab

CAS: 2437210-79-0 F: W:

Bafisontamab (EMB-01) is a bispecific antibody targeting EGFR and cMET with antitumor activity.
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Bioactivity Bafisontamab (EMB-01) is a bispecific antibody targeting EGFR and cMET with antitumor activity[1].
In Vivo Bafisontamab (EMB-01) 在 PDX 和 CDX 肿瘤模型中诱导的抗肿瘤活性明显强于抗 EGFR 单抗或抗 cMet 单抗。Bafisontamab 在抗 EGFR mAb 耐药肿瘤模型中表现出显著的抗肿瘤活性[1]。
Name Bafisontamab
CAS 2437210-79-0
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Reference [1]. Ren F, et al. EMB-01: An innovative bispecific antibody targeting EGFR and cMet on tumor cells mediates a novel mechanism to improve anti-tumor efficacy. Cancer Research, 2020, 80(16_Supplement): 528-528.