Bioactivity | Bafetinib is a potent and orally active Lyn/Bcr-Abl tyrosine kinase inhibitor. Bafetinib augments the activities of several proapoptotic Bcl-2 homology (BH)3-only proteins (Bim, Bad, Bmf and Bik) and induces apoptosis in Ph+ leukemia cells via Bcl-2 family-regulated intrinsic apoptosis pathway[1]. | ||||||||||||
Name | Bafetinib | ||||||||||||
CAS | 859212-16-1 | ||||||||||||
Formula | C30H31F3N8O | ||||||||||||
Molar Mass | 576.62 | ||||||||||||
Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
Storage |
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