Bioactivity | Bacitracin is a polypeptide antibiotic against staphylococcal and pathogenic protozoa infections. Bacitracin inhibits cell wall biosynthesis and permeability through binding to the undecaprenyl pyrophosphate. Bacitracin inhibits macromolecular synthesis. Bacitracin is also a protein disulfide isomerase (PDI) inhibitor[1][2][3]. |
Invitro | Bacitracin (64 μg/mL,24 h) 与粘菌素一起显示出对 S. aureus BA01611 的抗菌活性[1].Bacitracin (64 μg/mL,1或2 h) 破坏细胞表面,使其形成葡萄状细胞团,使得细胞边界模糊不清[1]。 |
Name | Bacitracin |
CAS | 1405-87-4 |
Formula | C66H103N17O16S |
Molar Mass | 1422.69 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | 4°C, protect from light *In solvent : -80°C, 6 months; -20°C, 1 month (protect from light) |