Bioactivity | Bach1-IN-1 (compound 236) is a potent Bach1 inhibitor. Bach1 is a transcription factor of the cap'n'collar type alkaline region leucine zipper factor family (CNC-bZip) that regulates mitochondrial metabolism and reduces glucose utilization. Bach1-IN-1 can be used for research in psoriasis, multiple sclerosis, and COPD[1][2]. |
Target | Bach1 |
Name | Bach1-IN-1 |
CAS | 1325721-55-8 |
Formula | C21H20F3N5O3S |
Molar Mass | 479.48 |
Appearance | Solid |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | 4°C, sealed storage, away from moisture *In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture) |
Reference | [1]. Attucks, et al. Bach 1 inhibitors in combination with Nrf2 activators and pharmaceutical compositions thereof. World Intellectual Property Organization, WO2016089648 A1 2016-06-09. [2]. Zhang X, et al. Bach1: Function, Regulation, and Involvement in Disease. Oxid Med Cell Longev. 2018 Oct 2;2018:1347969. |