| Bioactivity | BWC0977 is a potent inhibitor of topoisomerase that effects bacterial DNA replication via inhibition of DNA gyrase and topoisomerase IV. BWC0977 exhibits a minimum inhibitory concentration (MIC90) of 0.03–2 µg/mL against MDR Gram-negative bacteria[1]. |
| CAS | 2254567-00-3 |
| Formula | C22H21FN6O5 |
| Molar Mass | 468.44 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Shahul Hameed P, et al. BWC0977, a broad-spectrum antibacterial clinical candidate to treat multidrug resistant infections. Clinical Trial Nat Commun. 2024 Sep 18;15(1):8202. |
BWC0977
CAS: 2254567-00-3 F: C22H21FN6O5 W: 468.44
BWC0977 is a potent inhibitor of topoisomerase that effects bacterial DNA replication via inhibition of DNA gyrase and t
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