| Bioactivity | BWA-522 intermediate-1 is an intermediate in the synthesis of PROTAC BWA-522 (HY-149433) and serves as a ligand molecule for cereblon E3 ubiquitin ligase. BWA-522 is an orally active small molecule protein-targeting chimera (PROTAC) that has significant degradation effects on AR-FL and AR-V7[1]. | ||||||||||||
| Name | BWA-522 intermediate-1 | ||||||||||||
| CAS | 2241315-66-0 | ||||||||||||
| Formula | C19H19N3O5 | ||||||||||||
| Molar Mass | 369.37 | ||||||||||||
| Appearance | 固体 | ||||||||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
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| Reference | [1]. Arvinas Operations, et al. Indazole based compounds and associated methods of use. World Intellectual Property Organization, WO2021194879 A1 2021-09-30. |
BWA-522 intermediate-1
CAS: 2241315-66-0 F: C19H19N3O5 W: 369.37
BWA-522 intermediate-1 is an intermediate in the synthesis of PROTAC BWA-522 (HY-149433) and serves as a ligand molecule
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