| Bioactivity | BW-A 78U is a PDE4 inhibitor with an IC50 of 3 μM. | ||||||||||||
| Invitro | BW-A 78U is a PDE4 inhibitor with an IC50 of 3 μM. BW-A 78U fails to significantly inhibit arachidonate release. BW-A 78U is ineffective to inhibit the lipopolysaccharide (LPS)-induced TNF-α release[1]. | ||||||||||||
| Name | BW-A 78U | ||||||||||||
| CAS | 101155-02-6 | ||||||||||||
| Formula | C13H12FN5 | ||||||||||||
| Molar Mass | 257.27 | ||||||||||||
| Appearance | Solid | ||||||||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
| Storage |
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| Reference | [1]. Boichot E, et al. Anti-inflammatory activities of a new series of selective phosphodiesterase 4 inhibitors derivedfrom 9-benzyladenine. J Pharmacol Exp Ther. 2000 Feb;292(2):647-53. |