| Bioactivity | BTK ligand 10 is a Ligand for Target Protein for PROTAC. CDK8 ligand 1 can be used to synthesize (R)-NX-2127 (HY-153220A)[1]. |
| Formula | C10H13ClN4O |
| Molar Mass | 240.69 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Robbins DW, et al. Discovery and Preclinical Pharmacology of NX-2127, an Orally Bioavailable Degrader of Bruton's Tyrosine Kinase with Immunomodulatory Activity for the Treatment of Patients with B Cell Malignancies. J Med Chem. 2024 Feb 22;67(4):2321-2336. |