Bioactivity | BTK inhibitor 13 (compound 8) is a potent and selective Bruton's tyrosine kinase (BTK) inhibitor with an IC50 of 1.2 nM[1]. |
Target | 1.2 nM (BTK) |
Name | BTK inhibitor 13 |
CAS | 2376726-26-8 |
Formula | C29H26FN5O3 |
Molar Mass | 511.55 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Pulz R, et al. Design of Potent and Selective Covalent Inhibitors of Bruton's Tyrosine Kinase Targeting an Inactive Conformation. ACS Med Chem Lett. 2019 Sep 6;10(10):1467-1472. |