Bioactivity | BTK degrader-1 (compound 1) is a Bruton’s tyrosine kinase (BTK) bifunctional degrader that can be conjugated with CD79b. BTK degrader-1 (compound 1) has anti-tumor effect[1]. |
CAS | 2377645-56-0 |
Formula | C52H54F2N8O6 |
Molar Mass | 925.03 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Alan Zhang, et al. Design, Synthesis, and In Vitro and In Vivo Evaluation of Cereblon Binding Bruton’s Tyrosine Kinase (BTK) Degrader CD79bTargeted Antibody–Drug Conjugates. Bioconjug Chem. 2024 Feb 21;35(2):140-146. |