| Bioactivity | BTK-IN-27 (example 8) is a BTK inhibitor (IC50: 0.2 nM). BTK-IN-27 shows anti-proliferative activity in TMD8 cells (IC50: < 5 nM). BTK-IN-27 can be used for research of cancer, lymphoma, leukemia and immunological diseases[1]. |
| Target | 0.2 nM (BTK) |
| Name | BTK-IN-27 |
| CAS | 1841502-36-0 |
| Formula | C31H35N7O2 |
| Molar Mass | 537.66 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Mathew CALDER, et al. Pyrazolopyrimidine derivatives useful as inhibitors of bruton's tyrosine kinase. Patent. WO2015189620. |
BTK-IN-27
CAS: 1841502-36-0 F: C31H35N7O2 W: 537.66
BTK-IN-27 (example 8) is a BTK inhibitor (IC50: 0.2 nM). BTK-IN-27 shows anti-proliferative activity in TMD8 cells (IC50
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