| Bioactivity | BTK-IN-26 (compound 18) is a potent inhibitor of Bruton's tyrosine kinase (BTK) and its C481 mutant, with IC50 values of 0.7 and 0.8 nM for BTK and BTK C481S, respectively. BTK-IN-26 can be used for cancer and autoimmune diseases research[1]. |
| Name | BTK-IN-26 |
| CAS | 2762043-61-6 |
| Formula | C27H26D3FN6O3 |
| Molar Mass | 507.57 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Xiangyang Chen, et al. Heterocyclic compounds as btk inhibitors. Patent, WO2022037649A1. |
BTK-IN-26
CAS: 2762043-61-6 F: C27H26D3FN6O3 W: 507.57
BTK-IN-26 (compound 18) is a potent inhibitor of Bruton's tyrosine kinase (BTK) and its C481 mutant, with IC50 values of
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