Bioactivity | BRD4 degrader-1 (Compound ML 1-50) is a monovalent and covalent molecular glue BRD4 degrader. BRD4 degrader-1 targets DCAF16 (E3 ligase) and degrades both the long and short isoforms of BRD4 in cells[1]. |
Formula | C25H27ClN6O3S2 |
Molar Mass | 559.10 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Melissa Lim, et al. DCAF16-Based Covalent Handle for the Rational Design of Monovalent Degraders.ACS Central Science. DOI: 10.1021/acscentsci.4c00286 |