| Bioactivity | BRD-SF2 is a BRD4-targeted PROTAC degrader (DC50: 17.2 μM) (Blue: VHL ligand, black: linker, pink: BRD4 ligand)[1]. |
| Invitro | BRD-SF2 (1-75 μM，18 小时) 在 HEK293 细胞中诱导内源性 BRD4 降解[1]。 MCE has not independently confirmed the accuracy of these methods. They are for reference only. 0 --> BRD-SF2 相关抗体: |
| Formula | C59H76FN9O13S2 |
| Molar Mass | 1202.42 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Shah RR, et al. Structure-Guided Design and Optimization of Covalent VHL-Targeted Sulfonyl Fluoride PROTACs. J Med Chem. 2024 Mar 28;67(6):4641-4654. |