Bioactivity | BRCA2-RAD51-IN-1 (Compound 46) is a BRCA2-RAD51 inhibitor with an EC50 value of 28 μM. BRCA2-RAD51-IN-1 has antitumor activity[1]. |
Target | EC50: 28 μM (BRCA2-RAD51) |
Name | BRCA2-RAD51-IN-1 |
CAS | 2830213-53-9 |
Formula | C13H7BrF3N3O |
Molar Mass | 358.11 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Myers SH, et al. An 19F NMR fragment-based approach for the discovery and development of BRCA2-RAD51 inhibitors to pursuit synthetic lethality in combination with PARP inhibition in pancreatic cancer. Eur J Med Chem. 2023 Dec 31;265:116114. |