PeptideDB

BRCA2-RAD51-IN-1

CAS: 2830213-53-9 F: C13H7BrF3N3O W: 358.11

BRCA2-RAD51-IN-1 (Compound 46) is a BRCA2-RAD51 inhibitor with an EC50 value of 28 μM. BRCA2-RAD51-IN-1 has antitumor a
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Bioactivity BRCA2-RAD51-IN-1 (Compound 46) is a BRCA2-RAD51 inhibitor with an EC50 value of 28 μM. BRCA2-RAD51-IN-1 has antitumor activity[1].
Target EC50: 28 μM (BRCA2-RAD51)
Name BRCA2-RAD51-IN-1
CAS 2830213-53-9
Formula C13H7BrF3N3O
Molar Mass 358.11
Transport Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Reference [1]. Myers SH, et al. An 19F NMR fragment-based approach for the discovery and development of BRCA2-RAD51 inhibitors to pursuit synthetic lethality in combination with PARP inhibition in pancreatic cancer. Eur J Med Chem. 2023 Dec 31;265:116114.