| Bioactivity | BPDBA is a selective and noncompetitive betaine/GABA transporter (BGT-1) inhibitor with IC50s of 20 μM and 35 μM against human BGT-1 and mouse GAT2, respectively[1]. |
| In Vivo | BPDBA 被预测具有良好的口服吸收和血脑屏障穿透性能[1]。 |
| Name | BPDBA |
| CAS | 312281-74-6 |
| Formula | C19H20Cl2N2O |
| Molar Mass | 363.28 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Kragholm B, et al. Discovery of a subtype selective inhibitor of the human betaine/GABA transporter 1 (BGT-1) with a non-competitive pharmacological profile. Biochem Pharmacol. 2013 Aug 15;86(4):521-8. |