Bioactivity | BP-1-108 is a selective inhibitor of STAT5 (Ki=8.3 μM) with anticancer activity. BP-1-108 induces apoptosis of leukemia cells by inhibiting the phosphorylation of STAT5. BP-1-108 can be used in the study of acute myeloid leukemia and prostate cancer[1]. |
CAS | 1334492-85-1 |
Formula | C32H38N2O6S |
Molar Mass | 578.72 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Page, et al. "Small molecule STAT5-SH2 domain inhibitors exhibit potent antileukemia activity." Journal of medicinal chemistry 55.3 (2012): 1047-1055. |