PeptideDB

BODIPY FL Verapamil hydrochloride

CAS: 216571-88-9 F: C41H56BClF2N4O5 W: 769.17

BODIPY FL Verapamil hydrochloride is a fluorescent dye, it can be used as a molecular probe to label tissues and cells.
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This product is for research use only, not for human use. We do not sell to patients.

Bioactivity BODIPY FL Verapamil hydrochloride is a fluorescent dye, it can be used as a molecular probe to label tissues and cells. BODIPY FL Verapamil hydrochloride is a substrate for both ABCB1 and ABCC1[1][2].
Invitro BODIPY FL Verapamil hydrochloride (10 μM) can be incubated with removed tissue in phosphate buffered solution to demonstrate binding site[1].BODIPY FL Verapamil hydrochloride (0-100 nM) inhibits ABCB1 and ABCC1 efflux with loxapine, mometasone, nicardipine, pimozide and verapamil with IC50 values of 1.6-15.6 nM[2].
Name BODIPY FL Verapamil hydrochloride
CAS 216571-88-9
Formula C41H56BClF2N4O5
Molar Mass 769.17
Transport Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Reference [1]. Just S, et al. Histological demonstration of voltage dependent calcium channels on calcitonin gene-related peptide-immunoreactive nerve fibres in the mouse knee joint. Neurosci Lett. 2001 Oct 26;312(3):133-6. [2]. Strouse JJ, et al. Fluorescent substrates for flow cytometric evaluation of efflux inhibition in ABCB1, ABCC1, and ABCG2 transporters. Anal Biochem. 2013 Jun 1;437(1):77-87.