| Bioactivity | BNC210 (H-Ile-Trp-OH) is an orally active α7 nAChR negative alteration modulator (NAM) with no apparent side effects. BNC210 exhibits acute anxiolytic activity in rodent models of anxiety. BNC210 can be used in studies of generalised anxiety disorders[1]. | ||||||||||||
| Target | α7 nAChR. | ||||||||||||
| Name | BNC210 | ||||||||||||
| CAS | 13589-06-5 | ||||||||||||
| Formula | C17H23N3O3 | ||||||||||||
| Molar Mass | 317.38 | ||||||||||||
| Appearance | Solid | ||||||||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
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| Reference | [1]. Wise T, et al. Cholinergic modulation of disorder-relevant neural circuits in generalized anxiety disorder. Biological psychiatry, 2020, 87(10): 908-915. |