| Bioactivity | BMX-001, a novel redox-active metalloporphyrin, improves islet function and engraftment in a murine transplant model. BMX-001 reduces apoptosis in human and murine islets. BMX-001 significantly improves static-glucose stimulated insulin secretion (sGSIS) responses in murine islets. BMX-001 can significantly restore euglycemia in murine islet studies in the presence of the MnSOD. BMX-001 reduces the generation of ROS in a murine islet isolation and culture model[1]. |
| CAS | 1379783-91-1 |
| Formula | C64H76Cl5MnN8O4 |
| Molar Mass | 1253.54 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Antonio Bruni, et al. BMX-001, a novel redox-active metalloporphyrin, improves islet function and engraftment in a murine transplant model. Am J Transplant. 2018 Aug;18(8):1879-1889. |
BMX-001
CAS: 1379783-91-1 F: C64H76Cl5MnN8O4 W: 1253.54
BMX-001, a novel redox-active metalloporphyrin, improves islet function and engraftment in a murine transplant model. BM
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