| Bioactivity | BMS711939 is a selective agonist for peroxisome proliferator-activated receptor α (PPAR α), with EC50 of 4 nM and 4.5 μM, for human PPARα and human PPARγ. BMS711939 exhibits good pharmacokinetic characters in rats models. BMS711939 increases HDL cholesterol, reduces LDL cholesterol and triglycerides[1]. |
| CAS | 1000998-62-8 |
| Formula | C22H20ClFN2O6 |
| Molar Mass | 462.86 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Shi Y, et al., Discovery and Preclinical Evaluation of BMS-711939, an Oxybenzylglycine Based PPARα Selective Agonist. ACS Med Chem Lett. 2016 Apr 4;7(6):590-4. |
BMS711939
CAS: 1000998-62-8 F: C22H20ClFN2O6 W: 462.86
BMS711939 is a selective agonist for peroxisome proliferator-activated receptor α (PPAR α), with EC50 of 4 nM and 4.5
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