Bioactivity | BMS-986325 (anti-CD40) is a CD40 inhibitor, and can be used for primary Sjögren's syndrome research[1]. |
In Vivo | BMS-986325 (1 和 10 mg/kg,静脉注射,小鼠) 显示出 0.5-1.02 mL/d/kg 的低总血清清除率,有限的稳态分布容积 “Vss” 为 0.12 至 0.19 L/kg,且长效 表观消除半衰期为 118 至 183 h[1]。 MCE has not independently confirmed the accuracy of these methods. They are for reference only. |
Appearance | 液体 |
Transport | Shipping with dry ice. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Aaron YAMNIUKA, et al. ntagonistic cd40 monoclonal antibodies and uses thereof. Patent. WO2020106620A1 |