| Bioactivity | BMS-767778 is a selective DPP4 inhibitor, with a Ki of 0.9 nM[1]. |
| Target | Kis: 0.9 nM (DPP4), 4.9 μM (DPP8), 3.2 μM (DPP9). |
| Name | BMS-767778 |
| CAS | 915729-95-2 |
| Formula | C19H20Cl2N4O2 |
| Molar Mass | 407.29 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Pratik Devasthale, et al. Optimization of activity, selectivity, and liability profiles in 5-oxopyrrolopyridine DPP4 inhibitors leading to clinical candidate (Sa)-2-(3-(aminomethyl)-4-(2,4-dichlorophenyl)-2-methyl-5-oxo-5H-pyrrolo[3,4-b]pyridin-6(7H)-yl)-N,N-dimethylacetamide (BMS-767778). J Med Chem . 2013 Sep 26;56(18):7343-57. |