BMS-585248

CAS: 619331-12-3 F: C22H18FN7O3 W: 447.42

BMS-585248 is a potent, third-generation HIV-1 attachment inhibitor with a promising initial in vitro and in vivo pharma

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Bioactivity	BMS-585248 is a potent, third-generation HIV-1 attachment inhibitor with a promising initial in vitro and in vivo pharmacokinetic profile[1].
In Vivo	BMS-585248 (静脉注射 (1 mg/kg) 和口服 (5-200 mg/kg); 一次)具有良好的药代动力学特征，雄性大鼠静脉注射 (1mg /kg) 和口服 (5mg /kg) 后，AUC 值分别为 3220 nM·h 和 8064 nM·h。 Animal Model:
Name	BMS-585248
CAS	619331-12-3
Formula	C22H18FN7O3
Molar Mass	447.42
Transport	Room temperature in continental US; may vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Reference	[1]. Regueiro-Ren A, et al. Inhibitors of human immunodeficiency virus type 1 (HIV-1) attachment 13. Synthesis and profiling of a novel amminium prodrug of the HIV-1 attachment inhibitor BMS-585248. J Med Chem. 2013 Feb 28;56(4):1670-6.