Bioactivity | BMS-566394 is a potent inhibitor of tumor necrosis factor-α (TNF-α) converting enzyme (TACE) that helps reduce the production of TNF-α, thereby alleviating inflammation and immune-mediated diseases and can be used in the study of inflammatory and autoimmune diseases[1]. |
CAS | 503166-51-6 |
Formula | C22H21F3N4O4 |
Molar Mass | 462.42 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Sengupta P, et al. Synthesis, preliminary biological evaluation and molecular modeling of some new heterocyclic inhibitors of TACE[J]. European journal of medicinal chemistry, 2011, 46(11): 5549-5555. |