| Bioactivity | BMS-538305 hydrochloride is a potent and selective inhibitor of dipeptidyl peptidase IV (DPP-IV), exhibiting strong biological activity by forming a reversible covalent complex with the enzyme. BMS-538305 hydrochloride demonstrates its mechanism of action through the covalent attachment between the nitrile carbon of the inhibitor and the enzyme residue S630, as unveiled by the X-ray crystal structure analysis. |
| CAS | 841302-51-0 |
| Formula | C17H27ClN2O2 |
| Molar Mass | 326.86 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Involvement of DPP-IV catalytic residues in enzyme-saxagliptin complex formation |
BMS-538305 hydrochloride
CAS: 841302-51-0 F: C17H27ClN2O2 W: 326.86
BMS-538305 hydrochloride is a potent and selective inhibitor of dipeptidyl peptidase IV (DPP-IV), exhibiting strong biol
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