Bioactivity | BMS-496 is adualDGKα/ζlipid kinase inhibitor, with theIC50of 0.09 (DGKα) and 0.006 μM (DGKζ)[1]. |
Target | 0.09, 0.006 μM (DGKα,DGKζ). |
Name | BMS-496 |
CAS | 2407854-31-1 |
Formula | C26H22BrF2N5O3 |
Molar Mass | 570.39 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Wichroski M, et al. DGKα/ζ inhibitors combine with PD-1 checkpoint therapy to promote T cell-mediated antitumor immunity. Sci Transl Med. 2023;15(719):eadh1892. |