PeptideDB

BMS-193884

CAS: 176960-47-7 F: C20H17N3O4S W: 395.43

BMS-193884 is a selective, orally active, and competitive ETA antagonist with 10000-fold greater affinity for the human
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This product is for research use only, not for human use. We do not sell to patients.

Bioactivity BMS-193884 is a selective, orally active, and competitive ETA antagonist with 10000-fold greater affinity for the human ETA receptor (Ki=1.4 nM) than for the ETB receptor[1].
Name BMS-193884
CAS 176960-47-7
Formula C20H17N3O4S
Molar Mass 395.43
Transport Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Reference [1]. Murugesan N, et al. Biphenylsulfonamide endothelin receptor antagonists. 4. Discovery of N-[[2'-[[(4,5-dimethyl-3-isoxazolyl)amino]sulfonyl]-4-(2-oxazolyl)[1,1'-biphenyl]- 2-yl]methyl]-N,3,3-trimethylbutanamide (BMS-207940), a highly potent and orally act