Bioactivity | BMP agonist 2 (derivative I-9) is a potent bone-inducing cytokine. BMP agonist 2 promotes bone tissue production by increasing the proportion and activity of osteoblasts. BMP agonist 2 promotes osteoblast proliferation and differentiation through the BMP2-ATF4 signaling axis, in which ATF4 is a transcription factor closely related to osteoblast differentiation and bone formation. BMP agonist 2 can be used in the study of senile osteoporosis (SOP)[1]. | |||||||||
CAS | 1438900-88-9 | |||||||||
Formula | C16H19NO5 | |||||||||
Molar Mass | 305.33 | |||||||||
Appearance | 固体 | |||||||||
Transport | Room temperature in continental US; may vary elsewhere. | |||||||||
Storage |
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Reference | [1]. Zhou Z, et al. Efficacy, Mechanism, and Structure–Activity Relationship of 6-Methoxy Benzofuran Derivatives as a Useful Tool for Senile Osteoporosis[J]. Journal of Medicinal Chemistry, 2023, 66(3): 1742-1760. |