Bioactivity | BMAP-28 is an antibiotic peptide and an inducer of the mitochondrial permeability transition pore. BMAP-28 induces cell death through opening of the mitochondrial permeability transition pore. BMAP-28 can be used in study of microbial infections and cancer[1]. |
Invitro | BMAP-28 (3 µM; 10 min) 减弱 U937 细胞线粒体中的钙黄绿素荧光[1]。BMAP-28 在单细胞和分离的线粒体中引起线粒体内膜的去极化[1]。 Immunofluorescence[1] Cell Line: |
Name | BMAP-28 |
CAS | 184870-31-3 |
Sequence | Gly-Gly-Leu-Arg-Ser-Leu-Gly-Arg-Lys-Ile-Leu-Arg-Ala-Trp-Lys-Lys-Tyr-Gly-Pro-Ile-Ile-Val-Pro-Ile-Ile-Arg-Ile-NH2 |
Shortening | GGLRSLGRKILRAWKKYGPIIVPIIRI-NH2 |
Formula | C145H250N44O29 |
Molar Mass | 3073.81 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Risso A, et al. BMAP-28, an antibiotic peptide of innate immunity, induces cell death through opening of the mitochondrial permeability transition pore. Mol Cell Biol. 2002 Mar;22(6):1926-35. |