| Bioactivity | BMAP-28 is an antibiotic peptide and an inducer of the mitochondrial permeability transition pore. BMAP-28 induces cell death through opening of the mitochondrial permeability transition pore. BMAP-28 can be used in study of microbial infections and cancer[1]. |
| Invitro | BMAP-28 (3 µM; 10 min) 减弱 U937 细胞线粒体中的钙黄绿素荧光[1]。BMAP-28 在单细胞和分离的线粒体中引起线粒体内膜的去极化[1]。 Immunofluorescence[1] Cell Line: |
| Name | BMAP-28 |
| CAS | 184870-31-3 |
| Sequence | Gly-Gly-Leu-Arg-Ser-Leu-Gly-Arg-Lys-Ile-Leu-Arg-Ala-Trp-Lys-Lys-Tyr-Gly-Pro-Ile-Ile-Val-Pro-Ile-Ile-Arg-Ile-NH2 |
| Shortening | GGLRSLGRKILRAWKKYGPIIVPIIRI-NH2 |
| Formula | C145H250N44O29 |
| Molar Mass | 3073.81 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Risso A, et al. BMAP-28, an antibiotic peptide of innate immunity, induces cell death through opening of the mitochondrial permeability transition pore. Mol Cell Biol. 2002 Mar;22(6):1926-35. |
BMAP-28
CAS: 184870-31-3 F: C145H250N44O29 W: 3073.81
BMAP-28 is an antibiotic peptide and an inducer of the mitochondrial permeability transition pore. BMAP-28 induces cell
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