BMAP 28 (bovine)_product_DataBase

Bioactivity	BMAP 28 bovine is an antibacterial peptide. BMAP 28 bovine exhibits antimicrobial activity against gram-positive and gram-negative bacteria, by increasing cell membrane permeability, and causing leakage of cell contents. BMAP 28 bovine exhibits cytotoxicity to cancer cells and activated human lymphocytes. BMAP 28 bovine induces apoptosis through depolarization of mitochondrial membrane potential[1][2][3].
CAS	939963-76-5
Sequence	Gly-Gly-Leu-Arg-Ser-Leu-Gly-Arg-Lys-Ile-Leu-Arg-Ala-Trp-Lys-Lys-Tyr-Gly-Pro-Ile-Ile-Val-Pro-Ile-Ile-Arg-Ile-Gly
Shortening	GGLRSLGRKILRAWKKYGPIIVPIIRIG
Formula	C147H252N44O31
Molar Mass	3131.85
Transport	Room temperature in continental US; may vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Reference	[1]. Brogden KA, et al., Antimicrobial peptides in animals and their role in host defences. Int J Antimicrob Agents. 2003 Nov;22(5):465-78. [2]. Guo Y, et al., A bovine myeloid antimicrobial peptide (BMAP-28) and its analogs kill pan-drug-resistant Acinetobacter baumannii by interacting with outer membrane protein A (OmpA). Medicine (Baltimore). 2018 Oct;97(42):e12832. [3]. Risso A, et al., BMAP-28, an antibiotic peptide of innate immunity, induces cell death through opening of the mitochondrial permeability transition pore. Mol Cell Biol. 2002 Mar;22(6):1926-35.

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