| Bioactivity | BIO8898 is a potent CD40-CD154 inhibitor. BIO8898 inhibits soluble CD40L binding to CD40-Ig with an IC50 value of 25 µM. BIO8898 inhibits CD40L-induced apoptosis[1]. |
| Invitro | BIO8898 (0-100 µM; 3 days) inhibits CD40L-induced apoptosis in a dose-dependent manner[1]. Apoptosis Analysis[1] Cell Line: |
| Name | BIO8898 |
| Formula | C53H64N8O6 |
| Molar Mass | 909.13 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |