| Bioactivity | BIO7662 is a specific α4β1 antagonist. BIO7662 can be used to study α4β1 integrin-ligand interactions[1][2]. |
| Target | α4β1 |
| Name | BIO7662 |
| CAS | 327613-10-5 |
| Formula | C38H48N6O8S |
| Molar Mass | 748.89 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Egger LA, et al. A small molecule alpha4beta1/alpha4beta7 antagonist differentiates between the low-affinity states of alpha4beta1 and alpha4beta7: characterization of divalent cation dependence. J Pharmacol Exp Ther. 2003 Sep;306(3):903-13. [2]. Chen LL,et al. Evidence that ligand and metal ion binding to integrin alpha 4beta 1 are regulated through a coupled equilibrium. J Biol Chem. 2001 Sep 28;276(39):36520-9. |