Bioactivity | BIMAX2 acetate is a high affinity nuclear localization signal (NLS) peptide. BIMAX2 acetate can mimic the activity of the classical nuclear localization signal (cNLS) and competitively bind to importin α, thereby inhibiting the binding of cNLS-cargo proteins to importin α. BIMAX2 acetate can be used to study the role of RBBP4 in regulating nuclear import efficiency and cell senescence[1]. | ||||||
Sequence | Arg-Arg-Arg-Arg-Arg-Arg-Lys-Arg-Lys-Arg-Glu-Trp-Asp-Asp-Asp-Asp-Asp-Pro-Pro-Lys-Lys-Arg-Arg-Arg-Leu-Asp | ||||||
Shortening | RRRRRRKRKREWDDDDDPPKKRRRLD | ||||||
Formula | C146H254N64O41.xC2H4O2 | ||||||
Molar Mass | 3561.98 (free base) | ||||||
Appearance | 固体 | ||||||
Transport | Room temperature in continental US; may vary elsewhere. | ||||||
Storage | Sealed storage, away from moisture
*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture) |