| Bioactivity | BIBP3226 is a potent and selective neuropeptide Y Y1 (NPY Y1) and neuropeptide FF (NPFF) receptor antagonist, with Kis of 1.1, 79, and 108 nM for rNPY Y1, hNPFF2, and rNPFF, respectively. BIBP3226 displays anxiogenic-like effect[1][2]. |
| In Vivo | BIBP3226 (0.5, 5 μg; i.c.v.; male Wistar rats) induces an anxiogenic-like effect at the higher dose[1]. |
| Name | BIBP3226 |
| CAS | 159013-54-4 |
| Formula | C27H31N5O3 |
| Molar Mass | 473.57 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Mollereau C, et al. Agonist and antagonist activities on human NPFF(2) receptors of the NPY ligands GR231118 and BIBP3226. Br J Pharmacol. 2001 May;133(1):1-4. |