| Bioactivity | BFC1108 is a small molecule Bcl-2 functional converter. BFC1108 induces a conformational change in Bcl-2, resulting in the exposure of its BH3 domain both in vitro and in vivo. BFC1108 effectively induces apoptosis in Bcl-2 expressing cancers.[1]. |
| CAS | 692774-37-1 |
| Formula | C23H21ClN2O4 |
| Molar Mass | 424.88 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Kopparapu PR, et al. Identification and characterization of a small molecule Bcl-2 Functional Converter. Cancer Res Commun. 2024 Feb 8. |
BFC1108
CAS: 692774-37-1 F: C23H21ClN2O4 W: 424.88
BFC1108 is a small molecule Bcl-2 functional converter. BFC1108 induces a conformational change in Bcl-2, resulting in t
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