PeptideDB

BDP-13176

CAS: 2290660-61-4 F: C24H22Cl2N6O2 W: 497.38

BDP-13176 is a potent fascin 1 inhibitor, with a Kd of 90 nM and an IC50 of 240 nM. BDP-13176 has potential as an anti-m
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Bioactivity BDP-13176 is a potent fascin 1 inhibitor, with a Kd of 90 nM and an IC50 of 240 nM. BDP-13176 has potential as an anti-metastatic agent[1].
Invitro BDP-13176 (0-1 μM) inhibits fascin 1 bundling activity[1].
Name BDP-13176
CAS 2290660-61-4
Formula C24H22Cl2N6O2
Molar Mass 497.38
Appearance Solid
Transport Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Reference [1]. Francis S, et al. Structure-based design, synthesis and biological evaluation of a novel series of isoquinolone and pyrazolo[4,3-c]pyridine inhibitors of fascin 1 as potential anti-metastatic agents. Bioorg Med Chem Lett. 2019;29(8):1023-1029.