Bioactivity | BDP-13176 is a potent fascin 1 inhibitor, with a Kd of 90 nM and an IC50 of 240 nM. BDP-13176 has potential as an anti-metastatic agent[1]. | ||||||||||||
Invitro | BDP-13176 (0-1 μM) inhibits fascin 1 bundling activity[1]. | ||||||||||||
Name | BDP-13176 | ||||||||||||
CAS | 2290660-61-4 | ||||||||||||
Formula | C24H22Cl2N6O2 | ||||||||||||
Molar Mass | 497.38 | ||||||||||||
Appearance | Solid | ||||||||||||
Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
Storage |
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Reference | [1]. Francis S, et al. Structure-based design, synthesis and biological evaluation of a novel series of isoquinolone and pyrazolo[4,3-c]pyridine inhibitors of fascin 1 as potential anti-metastatic agents. Bioorg Med Chem Lett. 2019;29(8):1023-1029. |