Bioactivity | BDM91270 (compound 29) is an E. coli AcrAB-TolC efflux pump inhibitor with an EC90 of 0.6 μM for wild-type E. coli AcrB. BDM91270 can be used in the study of Escherichia coli drug resistance[1]. |
Target | EC90: 0.6 μM (AcrB). |
Name | BDM91270 |
CAS | 2892824-11-0 |
Formula | C17H21Cl3N4O2 |
Molar Mass | 419.73 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Compagne N, et al. Optimization of pyridylpiperazine-based inhibitors of the Escherichia coli AcrAB-TolC efflux pump. Eur J Med Chem. 2023 Jul 7;259:115630. |