| Bioactivity | BDM44768 is an inhibitior of IDE. BDM44768 exacerbates ER stress-induced IRE1 activation and promotes lipid accumulation in hepatocytes. BDM44768 potentiates activation of the IRE1 pathway in the liver and exacerbates liver lipid accumulation in an acute mice model of ER stress[1]. |
| CAS | 2011754-00-8 |
| Formula | C24H22FN5O3 |
| Molar Mass | 447.46 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Andres M, et al. Insulin-degrading enzyme inhibition increases the unfolded protein response and favours lipid accumulation in the liver. Br J Pharmacol. 2024 May 29. |
BDM44768
CAS: 2011754-00-8 F: C24H22FN5O3 W: 447.46
BDM44768 is an inhibitior of IDE. BDM44768 exacerbates ER stress-induced IRE1 activation and promotes lipid accumulation
Sales Email：peptidedb@qq.com
This product is for research use only, not for human use. We do not sell to patients.