Bioactivity | BDM19 binds and activates cytosolic BAX dimers, and prompts cell apoptosis either alone or in combination with BCL-2/BCL-XL inhibitor Navitoclax (HY-10087)[1]. |
Name | BDM19 |
CAS | 500273-31-4 |
Formula | C24H17IN2O3 |
Molar Mass | 508.31 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Gitego N, et al. Chemical modulation of cytosolic BAX homodimer potentiates BAX activation and apoptosis. Nat Commun. 2023;14(1):8381. Published 2023 Dec 16. |