| Bioactivity | BD-Oligo is an oligomer-specific fluorescent chemical probe. BD-Oligo preferentially identifies Aβ oligomer assemblies over monomers or fibrils by using diversity-directed fluorescent library (DOFL) screening and computational techniques. BD-Oligo exhibits dynamic oligomer monitoring capabilities during Aβ peptide fibril formation as Aβ is induced to form oligomers and ultimately fibrils over time. BD-Oligo also exhibits blood-brain barrier permeability with the ability to stain Aβ oligomers in vivo[1]. |
| CAS | 1357578-02-9 |
| Formula | C25H24BCl3F2N2O4 |
| Molar Mass | 571.64 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Teoh CL, et al. Chemical Fluorescent Probe for Detection of Aβ Oligomers. J Am Chem Soc. 2015 Oct 28;137(42):13503-9. |
BD-Oligo
CAS: 1357578-02-9 F: C25H24BCl3F2N2O4 W: 571.64
BD-Oligo is an oligomer-specific fluorescent chemical probe. BD-Oligo preferentially identifies Aβ oligomer assemblies
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