| Bioactivity | BChE-IN-39 (Compound 7c) is an inhibitor for butyrylcholinesterase (BChE) with an IC50 of 0.08 μM. (IC50=3.98 μM for AChE) BChE-IN-39 downregulates the GSK-3β expression, inhibits the hyperphosphorylation of tau protein[1]. |
| Formula | C29H23ClFN3O3 |
| Molar Mass | 515.96 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Noori M, et al., Isoindolinedione-Benzamide Pyridinium Derivatives for Targeting Alzheimer's Disease. ACS Omega. 2024 Nov 25;9(49):48032-48043. |