BChE-IN-34_product_DataBase

Bioactivity	BChE-IN-34 is a potent and selective butyrylcholinesterase (BChE) inhibitor with an IIC50 of 25 nM. BChE-IN-34 shows excellent selectivity against BChE over acetylcholinesterase. BChE-IN-34 has neuroprotective and antioxidant effects[1].
Invitro	BChE-IN-34 (compound 35a) 对 β-Amyloid (1-42)（HY-P1363A）聚集具有中等抑制效力，对 H2O2 和 β-Amyloid (1-42) 诱导的 SH-SY5Y 细胞损伤具有显著的神经保护作用[1] 。 MCE has not independently confirmed the accuracy of these methods. They are for reference only. 0 --> BChE-IN-34 相关抗体:
CAS	2215768-12-8
Formula	C21H19N5O2S2
Molar Mass	437.54
Transport	Room temperature in continental US; may vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Reference	[1]. Ebru Koçak Aslan, et al. Novel 1,2,4-triazole derivatives containing the naphthalene moiety as selective butyrylcholinesterase inhibitors: Design, synthesis, and biological evaluation. Arch Pharm (Weinheim). 2024 Jul 21:e2400406.

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