Bioactivity | ChE-IN-32 (compound 5d) is a potent and selective hBChE inhibitor with an IC50 value of 0.109 µM. BChE-IN-32 shows cytotoxicity. BChE-IN-32 has the potential for the research of Alzheimer's disease[1]. |
Invitro | BChE-IN-32 (compound 5d) (0-200 µM) 对 SH-SY5Y 和 HepG2 细胞具有细胞毒性,IC50 值分别为 110.0 和 42 µM[1]。 MCE has not independently confirmed the accuracy of these methods. They are for reference only. 0 --> BChE-IN-32 相关抗体: Cell Cytotoxicity Assay[1] Cell Line: |
Formula | C26H37N3O |
Molar Mass | 407.59 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Mezeiova E, et al. Morphing cholinesterase inhibitor amiridine into multipotent drugs for the treatment of Alzheimer's disease. Biomed Pharmacother. 2024 Apr;173:116399. |