| Bioactivity | BChE-IN-22 (compound 5A) is a selective eqBChE inhibitor (IC50: 0.53μM), has anti-inflammatory and neuroprotective activities. BChE-IN-22 can inhibit cell damage caused by Aβ25-35 (HY-P0128) and improve cognitive dysfunction caused by Scopolamine (HY-N0296)[1]. |
| Target | IC50: 0.53?μM (eqBChE), 7.8 μM (eeAChE) |
| Name | BChE-IN-22 |
| Formula | C25H31N3O5 |
| Molar Mass | 453.53 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Zhou Y, et al. Development of novel salicylic acid-donepezil-rivastigmine hybrids as multifunctional agents for the treatment of Alzheimer's disease. J Enzyme Inhib Med Chem. 2023 Dec;38(1):2231661. |